Total submissions: 2
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Pharm |
RCV000211326 | SCV000268338 | drug response | methotrexate response - Efficacy | 2021-03-24 | reviewed by expert panel | curation | PharmGKB Level of Evidence 2B: Variants in Level 2B clinical annotations are not in PharmGKB’s Tier 1 VIPs. These clinical annotations describe variant-drug combinations with a moderate level of evidence supporting the association. For example, the association may be found in multiple cohorts, but there may be a minority of studies that do not support the majority assertion. Level 2B clinical annotations must be supported by at least two independent publications. |
Invitae | RCV002054365 | SCV002405132 | benign | not provided | 2024-01-29 | criteria provided, single submitter | clinical testing |