ClinVar Miner

Submissions for variant NM_004281.3(BAG3):c.910-10C>G (rs727502899)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 1
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine RCV000150182 SCV000197100 uncertain significance not specified 2013-09-06 criteria provided, single submitter clinical testing The 910-10C>G variant in BAG3 has not been reported in individuals with cardiomy opathy or in large population studies. Although this variant is located in the 3 ' splice region, computational tools do not suggest an impact to splicing. Howev er, this information is not predictive enough to rule out pathogenicity. Additio nal information is needed to fully assess the clinical significance of the 910-1 0C>G variant.

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.