Total submissions: 3
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Gene |
RCV000424958 | SCV000535442 | likely benign | not provided | 2016-12-30 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Labcorp Genetics |
RCV002063626 | SCV002354803 | likely benign | RASopathy | 2023-11-24 | criteria provided, single submitter | clinical testing | |
Fulgent Genetics, |
RCV002488975 | SCV002796099 | likely benign | Cardiofaciocutaneous syndrome 1; Noonan syndrome 1; LEOPARD syndrome 3; Noonan syndrome 7; Melanoma, cutaneous malignant, susceptibility to, 1; Colorectal cancer; Lung cancer | 2021-11-13 | criteria provided, single submitter | clinical testing |