Total submissions: 3
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Laboratory for Molecular Medicine, |
RCV000037935 | SCV000061600 | likely pathogenic | Non-small cell lung carcinoma | 2011-10-04 | criteria provided, single submitter | clinical testing | Somatic BRAF variants have been identified in up to 3% of cases of lung adenocar cinoma (Davies 2002). The Val600Leu variant has been reported in an ovarian tum or cell line and in a urinary tract carcinoma (Pohl 2005, COSMIC). |
Database of Curated Mutations |
RCV000435048 | SCV000505027 | likely pathogenic | Melanoma | 2015-07-14 | no assertion criteria provided | literature only | |
Caryl and Israel Englander Institute for Precision Medicine, |
RCV002463625 | SCV002758656 | pathogenic | Myoepithelial tumor | 2022-11-01 | no assertion criteria provided | research |