ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.1936+8C>T

gnomAD frequency: 0.00004  dbSNP: rs776624068
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 5
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV001083369 SCV000253413 likely benign Hereditary diffuse gastric adenocarcinoma 2023-12-06 criteria provided, single submitter clinical testing
GeneDx RCV000437419 SCV000518082 likely benign not specified 2017-10-09 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Diagnostics, LLC DBA Color Health RCV000582008 SCV000689494 likely benign Hereditary cancer-predisposing syndrome 2017-09-05 criteria provided, single submitter clinical testing
Preventiongenetics, part of Exact Sciences RCV000679567 SCV000806649 likely benign not provided 2017-12-08 criteria provided, single submitter clinical testing
Women's Health and Genetics/Laboratory Corporation of America, LabCorp RCV000437419 SCV002548318 uncertain significance not specified 2022-05-27 criteria provided, single submitter clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.