ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.2295+15C>T

gnomAD frequency: 0.00001  dbSNP: rs754578936
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000425112 SCV000520411 likely benign not specified 2015-11-02 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Diagnostics, LLC DBA Color Health RCV001188665 SCV001355782 likely benign Hereditary cancer-predisposing syndrome 2019-09-16 criteria provided, single submitter clinical testing
Labcorp Genetics (formerly Invitae), Labcorp RCV003512040 SCV004277013 likely benign Hereditary diffuse gastric adenocarcinoma 2023-10-03 criteria provided, single submitter clinical testing

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