ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.2469A>C (p.Thr823=)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Diagnostics, LLC DBA Color Health RCV003585093 SCV004361276 likely benign Hereditary cancer-predisposing syndrome 2023-05-30 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004786984 SCV005406955 benign Hereditary diffuse gastric adenocarcinoma 2024-09-24 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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