ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.31C>T (p.Leu11=)

dbSNP: rs2152113973
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001466845 SCV001670856 likely benign Hereditary diffuse gastric adenocarcinoma 2020-03-18 criteria provided, single submitter clinical testing
GeneDx RCV004720916 SCV005326989 likely benign not provided 2018-11-21 criteria provided, single submitter clinical testing See Variant Classification Assertion Criteria.
Myriad Genetics, Inc. RCV001466845 SCV005407094 benign Hereditary diffuse gastric adenocarcinoma 2024-09-10 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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