ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.388-7C>G

gnomAD frequency: 0.00001  dbSNP: rs201402744
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000437745 SCV000528175 likely benign not specified 2017-06-28 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Labcorp Genetics (formerly Invitae), Labcorp RCV000527899 SCV000637827 likely benign Hereditary diffuse gastric adenocarcinoma 2024-01-26 criteria provided, single submitter clinical testing
Color Diagnostics, LLC DBA Color Health RCV000771305 SCV000903554 likely benign Hereditary cancer-predisposing syndrome 2018-01-01 criteria provided, single submitter clinical testing

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