ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.420C>T (p.Leu140=)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Diagnostics, LLC DBA Color Health RCV003585077 SCV004360449 likely benign Hereditary cancer-predisposing syndrome 2023-07-10 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004786982 SCV005407547 benign Hereditary diffuse gastric adenocarcinoma 2024-09-12 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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