ClinVar Miner

Submissions for variant NM_004360.5(CDH1):c.684C>T (p.Tyr228=)

dbSNP: rs1960744183
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV002211731 SCV002357279 likely benign Hereditary diffuse gastric adenocarcinoma 2021-07-06 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV002211731 SCV005405694 benign Hereditary diffuse gastric adenocarcinoma 2024-09-13 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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