ClinVar Miner

Submissions for variant NM_004484.4(GPC3):c.338-6_338-5dup

dbSNP: rs370737647
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Sema4, Sema4 RCV002258646 SCV002537454 likely benign Hereditary cancer-predisposing syndrome 2021-07-21 criteria provided, single submitter curation
Fulgent Genetics, Fulgent Genetics RCV002505900 SCV002808824 likely benign Wilms tumor 1; Simpson-Golabi-Behmel syndrome type 1 2021-12-06 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003933717 SCV004751995 benign GPC3-related disorder 2019-08-09 criteria provided, single submitter clinical testing This variant is classified as benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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