Total submissions: 1
| Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
|---|---|---|---|---|---|---|---|---|
| Ambry Genetics | RCV005267158 | SCV005933860 | uncertain significance | not specified | 2025-02-05 | criteria provided, single submitter | clinical testing | The c.908G>A (p.R303Q) alteration is located in exon 10 (coding exon 10) of the RRP9 gene. This alteration results from a G to A substitution at nucleotide position 908, causing the arginine (R) at amino acid position 303 to be replaced by a glutamine (Q). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear. |