ClinVar Miner

Submissions for variant NM_004985.5(KRAS):c.182A>T (p.Gln61Leu)

dbSNP: rs121913240
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 6
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000038258 SCV000061927 pathogenic Non-small cell lung carcinoma 2011-11-02 criteria provided, single submitter clinical testing
Genome Sciences Centre, British Columbia Cancer Agency RCV000202407 SCV000257452 likely pathogenic Medullary thyroid carcinoma 2015-09-01 no assertion criteria provided research
Database of Curated Mutations (DoCM) RCV000443593 SCV000504443 pathogenic Neoplasm of the large intestine 2015-07-14 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000038258 SCV000504444 pathogenic Non-small cell lung carcinoma 2014-10-02 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000437806 SCV000504445 pathogenic Thyroid tumor 2014-10-02 no assertion criteria provided literature only
Xiao lab, Department of Pathology, Memorial Sloan Kettering Cancer Center RCV000984128 SCV001132098 likely pathogenic Multiple myeloma 2019-08-31 no assertion criteria provided clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.