ClinVar Miner

Submissions for variant NM_005157.6(ABL1):c.944C>T (p.Thr315Ile) (rs121913459)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
OMIM RCV000013459 SCV000033706 pathogenic Leukemia, Philadelphia chromosome-positive, resistant to imatinib 2015-03-05 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000432136 SCV000505087 likely pathogenic Chronic myelogenous leukemia, BCR-ABL1 positive 2016-03-10 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000442565 SCV000505088 likely pathogenic Lymphoblastic leukemia, acute, with lymphomatous features 2015-07-14 no assertion criteria provided literature only

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