ClinVar Miner

Submissions for variant NM_005228.5(EGFR):c.2240T>C (p.Leu747Ser)

dbSNP: rs397517097
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 3
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000038392 SCV000062064 uncertain significance not specified 2008-07-30 no assertion criteria provided clinical testing
Database of Curated Mutations (DoCM) RCV000434243 SCV000505167 likely pathogenic Lung carcinoma 2016-05-13 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000443228 SCV000505168 likely pathogenic Squamous cell lung carcinoma 2014-12-26 no assertion criteria provided literature only

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.