ClinVar Miner

Submissions for variant NM_005228.5(EGFR):c.2484G>A (p.Leu828=)

gnomAD frequency: 0.00001  dbSNP: rs727504312
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Myriad Genetics, Inc. RCV005246673 SCV005895781 benign Lung cancer 2024-10-17 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000154376 SCV000204042 likely benign not specified 2007-04-16 no assertion criteria provided clinical testing

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