ClinVar Miner

Submissions for variant NM_005228.5(EGFR):c.2582T>A (p.Leu861Gln)

dbSNP: rs121913444
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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000150630 SCV000197955 drug response Tyrosine kinase inhibitor response 2006-10-28 no assertion criteria provided clinical testing
Database of Curated Mutations (DoCM) RCV000428294 SCV000504241 pathogenic Non-small cell lung carcinoma 2014-10-02 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000438538 SCV000504242 likely pathogenic Squamous cell lung carcinoma 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000420876 SCV000504243 likely pathogenic Lung adenocarcinoma 2016-05-31 no assertion criteria provided literature only
Key Laboratory of Carcinogenesis and Cancer Invasion, Central South University RCV000420876 SCV004042725 likely pathogenic Lung adenocarcinoma no assertion criteria provided clinical testing

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