ClinVar Miner

Submissions for variant NM_005343.4(HRAS):c.112-10C>T (rs727503092)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine RCV000150833 SCV000198372 likely benign not specified 2013-07-17 criteria provided, single submitter clinical testing 112-10C>T in Intron 2 of HRAS: This variant is not expected to have clinical sig nificance because it is not located within the splice consensus sequence and due to a lack of conservation of this nucleotide position across species, including mammals.
Invitae RCV000637313 SCV000758764 likely benign Costello syndrome 2017-12-12 criteria provided, single submitter clinical testing

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