ClinVar Miner

Submissions for variant NM_005343.4(HRAS):c.450+171C>T

gnomAD frequency: 0.00025  dbSNP: rs376091236
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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000156659 SCV000206380 not provided not specified 2014-07-01 no assertion provided clinical testing *14C>T in exon 5A of HRAS: This variant is not expected to have clinical significance because it is not located within the splice consensus sequence. It has been identified in 4/4316 of African American chromosomes by the NHLBI Exome Sequencing Project (http://evs.gs.washington.edu/EVS/; dbSNP rs376091236).

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