ClinVar Miner

Submissions for variant NM_005477.3(HCN4):c.2668C>T (p.Pro890Ser) (rs184801511)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000871274 SCV001012891 likely benign Brugada syndrome 8 2020-10-23 criteria provided, single submitter clinical testing
GeneDx RCV001545371 SCV001764695 likely benign not provided 2020-08-31 criteria provided, single submitter clinical testing Has not been previously published as pathogenic or benign to our knowledge; Reported in ClinVar (ClinVar Variant ID# 702282; Landrum et al., 2016); In silico analysis supports that this missense variant does not alter protein structure/function

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