ClinVar Miner

Submissions for variant NM_005883.3(APC2):c.3654C>T (p.Pro1218=)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV003558032 SCV004304625 benign not provided 2023-06-15 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003939117 SCV004761757 likely benign APC2-related disorder 2019-02-24 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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