ClinVar Miner

Submissions for variant NM_006096.3(NDRG1):c.663C>T (p.Pro221=) (rs377225752)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000423340 SCV000530455 likely benign not specified 2016-08-02 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Illumina Clinical Services Laboratory,Illumina RCV000654230 SCV000472134 uncertain significance Charcot-Marie-Tooth disease type 4 2016-06-14 criteria provided, single submitter clinical testing
Invitae RCV000654230 SCV000776120 likely benign Charcot-Marie-Tooth disease type 4 2017-12-27 criteria provided, single submitter clinical testing

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