ClinVar Miner

Submissions for variant NM_006231.3(POLE):c.2026+9C>T (rs373790607)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Counsyl RCV000409224 SCV000489466 likely benign Colorectal cancer, susceptibility to, 12 2016-10-07 criteria provided, single submitter clinical testing
GeneDx RCV000425321 SCV000521642 likely benign not specified 2017-07-19 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000409224 SCV000556412 benign Colorectal cancer, susceptibility to, 12 2018-01-03 criteria provided, single submitter clinical testing
PreventionGenetics RCV000425321 SCV000806735 benign not specified 2016-11-07 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000425321 SCV000601992 likely benign not specified 2017-05-24 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000759268 SCV000888500 likely benign not provided 2017-05-24 criteria provided, single submitter clinical testing

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