ClinVar Miner

Submissions for variant NM_006231.3(POLE):c.3378+10A>G (rs193075152)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000232584 SCV000289328 benign Colorectal cancer, susceptibility to, 12 2019-12-31 criteria provided, single submitter clinical testing
Counsyl RCV000232584 SCV000489177 likely benign Colorectal cancer, susceptibility to, 12 2016-08-30 criteria provided, single submitter clinical testing
GeneDx RCV000418442 SCV000521627 likely benign not specified 2017-07-31 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.

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