ClinVar Miner

Submissions for variant NM_006231.3(POLE):c.5130C>T (p.Asp1710=) (rs1340452589)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000565100 SCV000671447 likely benign Hereditary cancer-predisposing syndrome 2015-07-18 criteria provided, single submitter clinical testing Synonymous alterations with insufficient evidence to classify as benign
Integrated Genetics/Laboratory Corporation of America RCV000780643 SCV000918081 likely benign not specified 2019-08-29 criteria provided, single submitter clinical testing
Invitae RCV000878408 SCV001021310 likely benign Colorectal cancer, susceptibility to, 12 2019-12-31 criteria provided, single submitter clinical testing

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