ClinVar Miner

Submissions for variant NM_006270.5(RRAS):c.454-9T>A

dbSNP: rs1490597941
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001464025 SCV001667985 likely benign Noonan syndrome 2018-08-13 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV004704345 SCV005209867 likely benign not provided criteria provided, single submitter not provided
PreventionGenetics, part of Exact Sciences RCV003970605 SCV004777398 likely benign RRAS-related disorder 2020-01-16 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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