ClinVar Miner

Submissions for variant NM_006440.5(TXNRD2):c.1086+11C>T

gnomAD frequency: 0.00002  dbSNP: rs369332144
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000607498 SCV000724482 likely benign not specified 2017-11-07 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Labcorp Genetics (formerly Invitae), Labcorp RCV002532780 SCV003455313 likely benign Primary dilated cardiomyopathy 2023-11-17 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV004704120 SCV005208969 likely benign not provided criteria provided, single submitter not provided

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