ClinVar Miner

Submissions for variant NM_006514.3(SCN10A):c.4866T>C (p.Ser1622=) (rs6599242)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000248921 SCV000700615 benign not specified 2013-07-05 criteria provided, single submitter clinical testing
GeneDx RCV000248921 SCV000514479 benign not specified 2016-09-06 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Molecular Diagnostic Laboratory for Inherited Cardiovascular Disease,Montreal Heart Institute RCV000248921 SCV000740399 benign not specified 2016-06-10 criteria provided, single submitter clinical testing
PreventionGenetics RCV000248921 SCV000311520 benign not specified criteria provided, single submitter clinical testing

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