ClinVar Miner

Submissions for variant NM_006864.4(LILRB3):c.1375C>T (p.Leu459Phe)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV005364038 SCV006020574 uncertain significance not specified 2025-02-13 criteria provided, single submitter clinical testing The c.1375C>T (p.L459F) alteration is located in exon 8 (coding exon 8) of the LILRB3 gene. This alteration results from a C to T substitution at nucleotide position 1375, causing the leucine (L) at amino acid position 459 to be replaced by a phenylalanine (F). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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