ClinVar Miner

Submissions for variant NM_006939.4(SOS2):c.294A>G (p.Lys98=) (rs149713664)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000608019 SCV000716390 likely benign not specified 2017-03-03 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000952063 SCV001098530 likely benign not provided 2018-01-02 criteria provided, single submitter clinical testing
Women's Health and Genetics/Laboratory Corporation of America, LabCorp RCV000608019 SCV001361622 benign not specified 2019-12-09 criteria provided, single submitter clinical testing
Invitae RCV001431833 SCV001634594 likely benign Noonan syndrome 9 2020-10-15 criteria provided, single submitter clinical testing

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