ClinVar Miner

Submissions for variant NM_006939.4(SOS2):c.3490-13_3490-11dup

dbSNP: rs10658395
Minimum review status: Collection method:
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ClinVar version:
Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001518884 SCV001727659 benign Noonan syndrome 9 2023-11-10 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003966118 SCV004782257 likely benign SOS2-related disorder 2020-08-17 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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