Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Division of Medical Genetics, |
RCV001257501 | SCV001434326 | uncertain significance | Familial cancer of breast | 2019-11-06 | criteria provided, single submitter | clinical testing | To our knowledge, this sequence variant has not been previously reported in the literature. This variant is not present in the gnomAD databases https://gnomad.broadinstitute.org/. At this time, it is unknown whether or not this variant increases cancer risk; therefore, we interpret it as a variant of uncertain significance. PM2 |