ClinVar Miner

Submissions for variant NM_007294.3(BRCA1):c.1845_1846insG (p.Ser616fs) (rs1555591112)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) RCV000661108 SCV000783356 pathogenic Breast-ovarian cancer, familial 1 2017-12-15 reviewed by expert panel curation Variant allele predicted to encode a truncated non-functional protein.

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