Submissions for variant NM_007294.3(BRCA1):c.4097-10G>A (rs80358057)

Total submissions: 7

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
GeneDx	RCV000159886	SCV000209968	benign	not specified	2014-09-17	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics	RCV000724122	SCV000225366	uncertain significance	not provided	2014-07-09	criteria provided, single submitter	clinical testing
Invitae	RCV000234143	SCV000289792	likely benign	Hereditary breast and ovarian cancer syndrome	2018-01-03	criteria provided, single submitter	clinical testing
Counsyl	RCV000112252	SCV000489057	likely benign	Breast-ovarian cancer, familial 1	2016-08-09	criteria provided, single submitter	clinical testing
Color	RCV000580105	SCV000683150	likely benign	Hereditary cancer-predisposing syndrome	2015-07-30	criteria provided, single submitter	clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano	RCV000724122	SCV000887686	likely benign	not provided	2018-04-15	criteria provided, single submitter	clinical testing
Breast Cancer Information Core (BIC) (BRCA1)	RCV000112252	SCV000144973	uncertain significance	Breast-ovarian cancer, familial 1	2002-05-29	no assertion criteria provided	clinical testing