ClinVar Miner

Submissions for variant NM_007294.3(BRCA1):c.5152+7A>G (rs80358046)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000422346 SCV000530724 likely benign not specified 2016-08-17 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000559883 SCV000636013 likely benign not provided 2018-12-16 criteria provided, single submitter clinical testing
Color RCV000776170 SCV000911267 likely benign Hereditary cancer-predisposing syndrome 2017-12-08 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000083061 SCV000115135 benign Breast-ovarian cancer, familial 1 2011-05-10 no assertion criteria provided clinical testing
Breast Cancer Information Core (BIC) (BRCA1) RCV000083061 SCV000145348 uncertain significance Breast-ovarian cancer, familial 1 2004-02-20 no assertion criteria provided clinical testing

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