ClinVar Miner

Submissions for variant NM_007294.4(BRCA1):c.1966A>T (p.Asn656Tyr)

dbSNP: rs786203455
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
University of Washington Department of Laboratory Medicine, University of Washington RCV003157806 SCV003849599 likely benign Hereditary cancer-predisposing syndrome 2023-03-23 criteria provided, single submitter curation Missense variant in a coldspot region where missense variants are very unlikely to be pathogenic (PMID:31911673).
3DMed Clinical Laboratory Inc RCV000677803 SCV000803961 uncertain significance Breast neoplasm 2017-07-20 no assertion criteria provided clinical testing

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