Total submissions: 9
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Evidence- |
RCV001003380 | SCV001161515 | benign | Breast-ovarian cancer, familial, susceptibility to, 1 | 2019-06-18 | reviewed by expert panel | curation | IARC class based on posterior probability from multifactorial likelihood analysis, thresholds for class as per Plon et al. 2008 (PMID: 18951446). Class 1 based on posterior probability = 0.000012 |
Department of Pathology and Laboratory Medicine, |
RCV000500478 | SCV000591603 | likely benign | not specified | criteria provided, single submitter | clinical testing | ||
Color Diagnostics, |
RCV000584229 | SCV000688554 | likely benign | Hereditary cancer-predisposing syndrome | 2016-05-10 | criteria provided, single submitter | clinical testing | |
Labcorp Genetics |
RCV001518145 | SCV001726792 | benign | Hereditary breast ovarian cancer syndrome | 2023-09-12 | criteria provided, single submitter | clinical testing | |
National Health Laboratory Service, |
RCV001518145 | SCV002025905 | likely benign | Hereditary breast ovarian cancer syndrome | 2021-11-16 | criteria provided, single submitter | clinical testing | |
Gene |
RCV001799671 | SCV002044079 | likely benign | not provided | 2021-06-22 | criteria provided, single submitter | clinical testing | This variant is associated with the following publications: (PMID: 18424508, 22366370, 7606717, 18489799, 8531967) |
Sema4, |
RCV000584229 | SCV002537831 | benign | Hereditary cancer-predisposing syndrome | 2020-09-30 | criteria provided, single submitter | curation | |
Ce |
RCV001799671 | SCV004033561 | likely benign | not provided | 2024-07-01 | criteria provided, single submitter | clinical testing | BRCA1: BS3:Supporting, BS1 |
BRCAlab, |
RCV001003380 | SCV004243928 | benign | Breast-ovarian cancer, familial, susceptibility to, 1 | 2020-03-02 | no assertion criteria provided | clinical testing |