ClinVar Miner

Submissions for variant NM_007294.4(BRCA1):c.5454C>T (p.Asp1818=) (rs1555574705)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Health, Inc RCV000579674 SCV000683318 uncertain significance Hereditary cancer-predisposing syndrome 2020-01-15 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000985442 SCV001133634 uncertain significance not provided 2018-12-05 criteria provided, single submitter clinical testing
Ambry Genetics RCV000579674 SCV001186098 likely benign Hereditary cancer-predisposing syndrome 2018-02-23 criteria provided, single submitter clinical testing Synonymous alterations with insufficient evidence to classify as benign
Brotman Baty Institute,University of Washington RCV001077422 SCV001243353 not provided Breast-ovarian cancer, familial 1 no assertion provided in vitro
King Laboratory,University of Washington RCV001171389 SCV001251287 benign not specified 2019-09-01 no assertion criteria provided research

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