ClinVar Miner

Submissions for variant NM_007294.4(BRCA1):c.5551_5552insT (p.Asp1851fs)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Myriad Genetics, Inc. RCV004442560 SCV004930854 likely pathogenic Breast-ovarian cancer, familial, susceptibility to, 1 2023-12-27 criteria provided, single submitter clinical testing This variant is considered likely pathogenic. This variant creates a frameshift predicted to result in the incorporation of abnormal amino acid sequence into the protein product and abnormal protein elongation.

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