ClinVar Miner

Submissions for variant NM_007294.4(BRCA1):c.66A>G (p.Leu22=) (rs786202533)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000572074 SCV000665892 likely benign Hereditary cancer-predisposing syndrome 2016-12-22 criteria provided, single submitter clinical testing Synonymous alterations with insufficient evidence to classify as benign
Invitae RCV000932649 SCV001078334 likely benign not provided 2018-10-03 criteria provided, single submitter clinical testing
Color Health, Inc RCV000572074 SCV001348259 likely benign Hereditary cancer-predisposing syndrome 2019-09-03 criteria provided, single submitter clinical testing
Invitae RCV001498492 SCV001703242 likely benign Hereditary breast and ovarian cancer syndrome 2018-10-03 criteria provided, single submitter clinical testing
Brotman Baty Institute,University of Washington RCV001076494 SCV001242260 not provided Breast-ovarian cancer, familial 1 no assertion provided in vitro
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000932649 SCV001549377 uncertain significance not provided no assertion criteria provided clinical testing

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