ClinVar Miner

Submissions for variant NM_007327.4(GRIN1):c.570+10G>A

gnomAD frequency: 0.00078  dbSNP: rs200924771
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000428919 SCV000530224 likely benign not specified 2017-12-11 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Labcorp Genetics (formerly Invitae), Labcorp RCV000558371 SCV000651704 benign Intellectual disability, autosomal dominant 8 2024-01-27 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV004707253 SCV005228752 likely benign not provided criteria provided, single submitter not provided

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