Submissions for variant NM_012452.3(TNFRSF13B):c.291T>G (p.Pro97=)

gnomAD frequency: 0.03423  dbSNP: rs35062843

Total submissions: 6

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
PreventionGenetics, part of Exact Sciences	RCV000252622	SCV000311930	benign	not specified		criteria provided, single submitter	clinical testing
Illumina Laboratory Services, Illumina	RCV000359099	SCV000400918	likely benign	Common Variable Immune Deficiency, Dominant	2016-06-14	criteria provided, single submitter	clinical testing
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine	RCV000252622	SCV000540557	benign	not specified	2016-03-29	criteria provided, single submitter	clinical testing	Variant identified in a genome or exome case(s) and assessed due to predicted null impact of the variant or pathogenic assertions in the literature or databases. Disclaimer: This variant has not undergone full assessment. The following are preliminary notes: Frequency
Labcorp Genetics (formerly Invitae), Labcorp	RCV000536341	SCV000649855	benign	Immunodeficiency, common variable, 2	2025-02-03	criteria provided, single submitter	clinical testing
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	RCV004703543	SCV000884704	benign	not provided	2024-10-11	criteria provided, single submitter	clinical testing
Breakthrough Genomics, Breakthrough Genomics	RCV004703543	SCV005212254	likely benign	not provided		criteria provided, single submitter	not provided