Submissions for variant NM_014000.3(VCL):c.875-24T>A

gnomAD frequency: 0.65590  dbSNP: rs1908339

Total submissions: 9

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Eurofins Ntd Llc (ga)	RCV000596456	SCV000703472	benign	not specified	2016-12-14	criteria provided, single submitter	clinical testing
GeneDx	RCV000830413	SCV000972148	benign	not provided	2018-06-14	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	RCV000830413	SCV001159484	benign	not provided	2022-09-13	criteria provided, single submitter	clinical testing
Labcorp Genetics (formerly Invitae), Labcorp	RCV001520452	SCV001729546	benign	Dilated cardiomyopathy 1W	2025-02-03	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002245033	SCV002514449	benign	Hypertrophic cardiomyopathy 15	2021-12-05	criteria provided, single submitter	clinical testing
Breakthrough Genomics, Breakthrough Genomics	RCV000830413	SCV005315850	benign	not provided		criteria provided, single submitter	not provided
Genome Diagnostics Laboratory, University Medical Center Utrecht	RCV000596456	SCV001930473	benign	not specified		no assertion criteria provided	clinical testing
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+	RCV000596456	SCV001952630	benign	not specified		no assertion criteria provided	clinical testing
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	RCV000596456	SCV001965148	benign	not specified		no assertion criteria provided	clinical testing