ClinVar Miner

Submissions for variant NM_014233.4(UBTF):c.2003G>T (p.Arg668Leu)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
PreventionGenetics, part of Exact Sciences RCV004726276 SCV005340132 uncertain significance UBTF-related disorder 2024-06-03 no assertion criteria provided clinical testing The UBTF c.2003G>T variant is predicted to result in the amino acid substitution p.Arg668Leu. To our knowledge, this variant has not been reported in the literature or in a large population database, indicating this variant is rare. At this time, the clinical significance of this variant is uncertain due to the absence of conclusive functional and genetic evidence.

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