ClinVar Miner

Submissions for variant NM_014795.4(ZEB2):c.798G>C (p.Gly266=) (rs34961586)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000148005 SCV000169862 benign not specified 2013-01-22 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genetic Services Laboratory, University of Chicago RCV000148005 SCV000195503 benign not specified 2013-02-08 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000148005 SCV000231740 benign not specified 2015-05-15 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000266678 SCV000416648 likely benign Mowat-Wilson syndrome 2016-06-14 criteria provided, single submitter clinical testing
Invitae RCV000266678 SCV000555867 benign Mowat-Wilson syndrome 2019-12-31 criteria provided, single submitter clinical testing
Ambry Genetics RCV000719880 SCV000850751 likely benign History of neurodevelopmental disorder 2016-08-16 criteria provided, single submitter clinical testing Synonymous alterations with insufficient evidence to classify as benign

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