ClinVar Miner

Submissions for variant NM_015117.3(ZC3H3):c.1964G>C (p.Ser655Thr)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV005313644 SCV005969323 uncertain significance not specified 2025-01-09 criteria provided, single submitter clinical testing The c.1964G>C (p.S655T) alteration is located in exon 7 (coding exon 7) of the ZC3H3 gene. This alteration results from a G to C substitution at nucleotide position 1964, causing the serine (S) at amino acid position 655 to be replaced by a threonine (T). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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