ClinVar Miner

Submissions for variant NM_016373.4(WWOX):c.835C>T (p.Arg279Cys) (rs77314072)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics RCV000224551 SCV000280840 likely benign not provided 2015-10-28 criteria provided, single submitter clinical testing Converted during submission to Likely benign.
GeneDx RCV000430448 SCV000524605 benign not specified 2017-12-22 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000224551 SCV000561078 benign not provided 2019-02-22 criteria provided, single submitter clinical testing
Athena Diagnostics Inc RCV000224551 SCV000844907 benign not provided 2018-08-07 criteria provided, single submitter clinical testing

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