ClinVar Miner

Submissions for variant NM_018372.4(LRIF1):c.1387A>G (p.Ser463Gly)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004938161 SCV005610452 uncertain significance not specified 2024-10-04 criteria provided, single submitter clinical testing The c.1387A>G (p.S463G) alteration is located in exon 2 (coding exon 2) of the LRIF1 gene. This alteration results from a A to G substitution at nucleotide position 1387, causing the serine (S) at amino acid position 463 to be replaced by a glycine (G). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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