ClinVar Miner

Submissions for variant NM_020125.3(SLAMF8):c.436T>G (p.Cys146Gly)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004676488 SCV005167255 uncertain significance not specified 2024-04-09 criteria provided, single submitter clinical testing The c.436T>G (p.C146G) alteration is located in exon 3 (coding exon 3) of the SLAMF8 gene. This alteration results from a T to G substitution at nucleotide position 436, causing the cysteine (C) at amino acid position 146 to be replaced by a glycine (G). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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